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Pharmaceutical Intermediate IMIDAZO 1 2-B PYRIDAZINE CAS 766-55-2

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  • CAS No.766-55-2,Imidazo[1,2-b]pyridazine Suppliers

    Pharmaceutical Intermediate, Imidazo[1,2-b]pyridazine CAS:766-55-2. Min.Order: 1 Kilogram. FOB Price: USD 32.7-35.6/Kilogram. Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales.

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  • CAS 766-55-2 Imidazo[1,2-b]pyridazine products

    Imidazo[1,2-b]pyridazine CAS NO.766-55-2. FOB Price:1 USD/Kilogram Min.Order:1 Kilogram Supply Ability:5000 Kilogram/Month Appearance:detailed see specifications Purity:99(%) Packaging:ribbon of gold foil Usage:Used as intermediate for medicine, dye, fungicide and photoinitiator Brand:yanxiyanxi

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  • Imidazo[1,2-b]pyridazine CAS#: 766-55-2

    2021-4-2 · ChemicalBook provide Chemical industry users with Imidazo[1,2-b]pyridazine Boiling point Melting point,Imidazo[1,2-b]pyridazine Density MSDS Formula Use,If You also need to Imidazo[1,2-b]pyridazine Other information,welcome to contact us.

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  • 18087-73-5|3-Bromoimidazo[1,2-b]pyridazine| Ambeed

    2013-3-9 · 产品英文名称: Imidazo[1,2-b]pyridazine 有效期: 一个月 产品描述 Appearance: white crystals Assay: ≥98% Usage: An intermediate in the synthesis of pharmaceutical raw materials. 关键字: 公司简介 Wuhan Hezhong Bio-Chemical Co., Ltd. belong to ...

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  • 1383481-11-5|7-Chloroimidazo[1,2-b]pyridazine| Ambeed

    The imidazo [1,2-b] pyridazine (6.0 g, 50.4 mmol), NBS (6.0 g, 75.6 mmol) and a catalytic amount of AIBN were added to 50 mL of chloroform and the reaction was heated to reflux for 2 hours, The reaction solution was cooled to room temperature when the raw material disappeared with the TLC detection of the reaction process, and a precipitate ...

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  • sell active pharmaceutical ingredient,bulk medicine,API ...

    Yield Reaction Conditions Operation in experiment; 59%: at 100℃; for 16.00 h; A solution of 5-chloropyridazin-3-amine (14.4 g, 111 mmol) and chloroacetaldehyde (81 mL, 556 mmol) in 2-propanol (150 mL) was heated at 100 °C for 16 h.

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  • Anti-biotics | Sandoo Pharmaceutical

    Quality sell active pharmaceutical ingredient,bulk medicine,API,pharmaceutical intermediate - find quality New product, Organic Intermediate & New product from zibo saitong polyurethane co.ltd of China Suppliers - 153606040.

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  • pyridazine | Sigma-Aldrich

    Sandoo Pharmaceutical is a professional anti-biotics intermediate manufacturer, producing high quality anti-biotics intermediate, inquiry us. 0086-574-87934126 [email protected]

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  • Pyridazine | Chemical Product Catalog - Chemsrc

    Search results for pyridazine at Sigma-Aldrich. Compare Products: Select up to 4 products. *Please select more than one item to compare

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  • 18087-73-5|3-Bromoimidazo[1,2-b]pyridazine| Ambeed

    2013-3-9 · 产品英文名称: Imidazo[1,2-b]pyridazine 有效期: 一个月 产品描述 Appearance: white crystals Assay: ≥98% Usage: An intermediate in the synthesis of pharmaceutical raw materials. 关键字: 公司简介 Wuhan Hezhong Bio-Chemical Co., Ltd. belong to ...

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  • 1383481-11-5|7-Chloroimidazo[1,2-b]pyridazine| Ambeed

    The imidazo [1,2-b] pyridazine (6.0 g, 50.4 mmol), NBS (6.0 g, 75.6 mmol) and a catalytic amount of AIBN were added to 50 mL of chloroform and the reaction was heated to reflux for 2 hours, The reaction solution was cooled to room temperature when the raw material disappeared with the TLC detection of the reaction process, and a precipitate ...

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  • Pyridazine as a privileged structure: An updated review on ...

    Yield Reaction Conditions Operation in experiment; 59%: at 100℃; for 16.00 h; A solution of 5-chloropyridazin-3-amine (14.4 g, 111 mmol) and chloroacetaldehyde (81 mL, 556 mmol) in 2-propanol (150 mL) was heated at 100 °C for 16 h.

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  • c6h5n3, c6h5n3 Suppliers and Manufacturers at buathiphotel.com

    2021-1-1 · The indole substituted imidazo [1,2-b]pyridazine compound 83 displayed high cytotoxicity toward A375 and Colo-205 human cancer cell lines with the IC 50 values of 14, 21 nM, respectively . The replacement of indole group in molecule 83 with other aromatic ring resulted in weaker anticancer activity.

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  • China Organic Intermediate,Pharmaceutical Intermediates ...

    buathiphotel.com offers 2,105 c6h5n3 products. A wide variety of c6h5n3 options are available to you,

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  • Intermediates for APIs (Active Pharmaceutical Ingredients ...

    Ribofuranose CAS 6974-32-9 Pharmaceutical Intermediate. 1 2 3-Triacetyl-5-deoxy-D-ribose CAS NO 62211-93-2. Chlorotrimethylsilane 99% CAS NO 75-77-4. Dibutyl lauroyl glutamide 98% CAS NO 63663-21-8. 6-Methoxy-1-indanone 98% CAS NO 13623-25-1. Local Anesthesia Pramoxine HCl CAS 637-58-1. high purity CAS 120-14-9 Pharmaceutical Intermediates

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  • Eastsky Pharm (Anhui) Technology Co., Ltd. - Sanmen ...

    BPS has well-established relationships with manufacturers of active pharmaceutical ingredients within the territory of the European Union to: Propose new intermediates to developEvaluate the sales potencial of intermediates in development phasePromote and sell products in …

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  • Benzohydrazide - an overview | ScienceDirect Topics

    IUPAC Name: hexanedihydrazide | CAS Registry Number: 1071-93-8 Synonyms: Adipic dihydrazide, Adipohydrazide, Adipic acid dihydrazide, Adip dihydr, Adipyl hydrazide ...

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  • DRUG SYNTHESIS INTERNATIONAL: TINIB SERIES 2/3

    Benzpiperylon (7.1.43) and piperylon (7.1.44) were prepared starting from 1-methylpiperidin-4-one (7.1.36), which was converted to benzoylhydrazone (7.1.38) on reflux with benzohydrazide (7.1.37) in ethanol.Hydrogenation of the obtained product in acetic acid on Adams’s catalyst (PtO 2) followed by hydrolysis of obtained (7.1.39) on boiling with hydrochloric acid, which gave N ...

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  • Synthesis, Characterization, and Application of Chiral ...

    2019-5-26 · A novel structural class of picornavirus inhibitors comprising an imidazo[1,2-b]pyridazine nucleus has been discovered. 2-Aminoimidazo[1,2-b]pyridazines, e.g., I, were designed and synthesized in an effort to identify potent broad-spectrum antirhinoviral agents. A practical synthetic route to this chem. scaffold has been developed.

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  • ec.europa.eu

    Used as a pharmaceutical intermediate for the manufacture of Active Pharmaceutical Ingredients (API’s) ... (CAS RN 51707-55-2) ... Imidazo[1,2-b] pyridazine-hydrochloride (CAS RN 18087-70-2) fr. Chlorohydrate d’imidazo [1,2-b] pyridazine (CAS RN 18087-70-2) ...

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  • Ticagrelor Intermediates,Saxagliptin Intermediates ...

    943320-61-4,PONATINIB Intermediate,3-Ethynylimidazo[1,2-b]pyridazine. Axitinib Intermediates 70315-70-7. 635702-60-2, Pazopanib HCL Intermediates. CAS NO. 635702-60-2 Pazopanib Intermediate. 1335210-24-6, Cabotegravir Intermediate. CAS 1335210-24-6, Cabotegravir Intermediate. 1335210-25-7, Cabotegravir Intermediate. 1335210-25-7,Intermediate of ...

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  • ChemInform Abstract: Synthesis and Evaluation of ...

    Request PDF | On Mar 1, 2012, I.G. Rathish and others published ChemInform Abstract: Synthesis and Evaluation of Anticancer Activity of Some Novel 6-Aryl-2 …

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  • PD-1/PD-L1 inhibitors - Gilead Sciences, Inc.

    The invention claimed is: 1. A compound which is: or a pharmaceutically acceptable salt thereof. 2. A compound which is: or a pharmaceutically acceptable salt thereof. 3. A compound which is: or a pharmaceutically acceptable salt thereof. 4. A pharmaceutical composition comprising the compound of claim 1 or a pharmaceutically acceptable salt thereof, and at least one …

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  • (PDF) Synthesis and Antimicrobial Studies of Some Novel ...

    Both 3‐aminothieno[2,3‐b]pyridine‐2‐carboxamide derivative 4 and bis(3‐aminothieno[2,3‐b]pyridine‐2‐carboxamide) derivative 6 are prepared, starting with pyridine‐2(1H)‐thione ...

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  • DRUG SYNTHESIS INTERNATIONAL: TINIB SERIES 2/3

    2021-4-6 · The free base (Formula 1, 0.895 mg, 2 mmol) was mixed with 10 mL of MeOH and seeded with 33 mg of a mono-isethionate salt of the compound of Formula 1 (Form B). Then 5.6 mL of a 0.375 M solution of isethionic acid in MeOH (2.1 mmol) was added in 10 even portions over 75 min time period.

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  • 7-AZASPIRO[3

    2009-10-28 · DETAILED DESCRIPTION. TECHNICAL FIELD . The present invention relates to 7-azaspiro[3.5]nonane-7-carboxamide compounds and the pharmaceutically acceptable salts of …

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  • Progress in Medicinal Chemistry : Volume 29 - SILO.PUB

    Lipophilic arylmethyl 2-substituents were favoured in vitro (0.01-0.2 pM) and topically (1 0- 50 pg/ear), although even 2-methyl- 1-naphthol was selective (but less potent) for 5-LO. The nature of the aryl group was relatively unimportant (except that carboxylic acid bearing rings were disfavoured), as was substitution in the non-phenolic ring.

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  • ec.europa.eu

    Used as a pharmaceutical intermediate for the manufacture of Active Pharmaceutical Ingredients (API’s) ... (CAS RN 51707-55-2) ... Imidazo[1,2-b] pyridazine-hydrochloride (CAS RN 18087-70-2) fr. Chlorohydrate d’imidazo [1,2-b] pyridazine (CAS RN 18087-70-2) ...

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  • Shanghai Fuxin Pharmaceutical Co., Ltd. (Page 20 ...

    2021-3-6 · imidazo[1,2-a]pyrazine cas:274-79-3 : imidazo[1,2-a]pyridin-3-yl-acetic acid cas:17745-04-9 : imidazo[1,2-a]pyridin-6-amine cas:235106-53-3 : imidazo[1,2-a]pyridin-6-ylboronic acid cas:913835-63-9 : imidazo[1,2-a]pyridine-7-carbaldehyde cas:136117-73-2 : imidazo[1,2-a]pyridine-8-carboxylic acid cas:133427-08-4 : imidazo[1,2-a]pyrimidine cas:274 ...

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  • Research Publications - Bristol-Myers Squibb

    2021-4-9 · Cytometry B Clin Cytom. 2020 Dec 1. doi: 10.1002/cyto.b.21970. Online ahead of print. PMID: 33259706 Patterns of drug release as a function of drug loading from amorphous solid dispersions: A comparison of five different polymers. Saboo S, Moseson DE, Kestur US, Taylor LS. Eur J Pharm Sci. 2020 Dec 1;155:105514. doi: 10.1016/j.ejps.2020.105514.

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  • US Patent for Heteroaryl pyridone and aza-pyrodine ...

    Heteroaryl pyridone and aza-pyridone compounds are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using heteroaryl pyridone and aza-pyridone compounds for in vitro, in situ, and in vivo diagnosis, and …

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  • US 6759554 B2 - Copper-catalyzed Formation Of Carbon ...

    The Lens serves almost all the patents and scholarly work in the world as a free, open and secure digital public good, with user privacy a paramount focus.

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  • Progress in Medicinal Chemistry : Volume 29 - SILO.PUB

    Lipophilic arylmethyl 2-substituents were favoured in vitro (0.01-0.2 pM) and topically (1 0- 50 pg/ear), although even 2-methyl- 1-naphthol was selective (but less potent) for 5-LO. The nature of the aryl group was relatively unimportant (except that carboxylic acid bearing rings were disfavoured), as was substitution in the non-phenolic ring.

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  • Oxidative Cyclization in Natural Product Biosynthesis ...

    2016-12-12 · From there, it was suggested that a C 15-C 19 cyclization step can yield the C 20 tertiary carbocation 102, which can undergo concerted 1,2-alkyl shift and 1,3-hydride shift to yield a new C 15 tertiary carbocation 103. The origin of the two hydrogen atoms on C 19 (shown in blue) is consistent with prior labeling studies using C 3-2 H-labeled ...

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  • Open University

    2015-6-19 · 748 38527. 585 39317. 519 43025. 288 43014. 255 37725. 204 39318. 203 38010. 174 41974. 173 43015. 146 27298. 144 35000. 139 36234. 129 32728. 120 40447. 120 36233 ...

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  • Q - Ferdowsi University of Mashhad

    موارد یافت شده: 4281 1 - A Vibrational Technique for In Vitro Intraoperative Prosthesis Fixation Monitoring (چکیده) 2 - A three-dimensional micromechanical model of brain white matter with histology-informed probabilistic distribution of axonal fibers (چکیده) 3 - Micromechanics of brain white matter tissue: A fiber-reinforced hyperelastic model using embedded element ...

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  • Shanghai Fuxin Pharmaceutical Co., Ltd. (Page 20 ...

    2021-3-6 · imidazo[1,2-a]pyrazine cas:274-79-3 : imidazo[1,2-a]pyridin-3-yl-acetic acid cas:17745-04-9 : imidazo[1,2-a]pyridin-6-amine cas:235106-53-3 : imidazo[1,2-a]pyridin-6-ylboronic acid cas:913835-63-9 : imidazo[1,2-a]pyridine-7-carbaldehyde cas:136117-73-2 : imidazo[1,2-a]pyridine-8-carboxylic acid cas:133427-08-4 : imidazo[1,2-a]pyrimidine cas:274 ...

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  • The Inhibitor Index - Routledge Handbooks

    C21. This selective PRMT inhibitor (FW = 2166.94 g/mol; CAS 1229236-78-5; Soluble: 2 mg/mL H 2 O; Sequence: Acetyl-SGXGKGGKGLGKGG AKRHRKV, where X = N 5-(2-chloro-l-iminoethyl)]-ornithine)) targets Protein Arginine Methy 1-Transferase 1, or PRMT1 (IC 50 =1.8 μM), with 5x selectivity for PRMT1 over PRMT6 and >250x over PRMT3 and CARM1 (1). Protein arginine …

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  • Progress in Medicinal Chemistry : Volume 29 - SILO.PUB

    2013-7-1 · 型号:1 品牌:进口 应用:工业设备 单价: ¥1

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  • Iron catalysis in organic synthesis. - PDF Download Free

    Lipophilic arylmethyl 2-substituents were favoured in vitro (0.01-0.2 pM) and topically (1 0- 50 pg/ear), although even 2-methyl- 1-naphthol was selective (but less potent) for 5-LO. The nature of the aryl group was relatively unimportant (except that carboxylic acid bearing rings were disfavoured), as was substitution in the non-phenolic ring.

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  • Oxidative Cyclization in Natural Product Biosynthesis ...

    Benzotriazoles gave exclusively N-1 substitution (eq a). 4-Phenyl-2H-1,2,3-triazole and 4-benzoyl-5-phenyl-2H-1,2,3-triazole predominantly led to the N-2 substituted products (eq b). In addition, three examples of 1,1-disubstituted propargylic alcohols as substrates have been reported to give the corresponding propargylated 1,2,3triazoles.

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  • 4-aminoquinazoline antagonists of selective sodium and ...

    2016-12-12 · From there, it was suggested that a C 15-C 19 cyclization step can yield the C 20 tertiary carbocation 102, which can undergo concerted 1,2-alkyl shift and 1,3-hydride shift to yield a new C 15 tertiary carbocation 103. The origin of the two hydrogen atoms on C 19 (shown in blue) is consistent with prior labeling studies using C 3-2 H-labeled ...

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  • US 2009/0264300 A1 - Enzymatic Encoding Methods For ...

    FIELD: chemistry. SUBSTANCE: present invention relates to a quinazoline compound of formula or its pharmaceutically acceptable salts, used as inhibitors of potential-dependant sodium and calcium channels, where R 1, R 2, R 3, R 5a, R 5, y and x are defined in the formula of invention.The invention also relates to a pharmaceutical composition containing the disclosed compound and …

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  • Montana DEQ > Home

    The generic term amino acid comprises both natural and non-natural amino acids. Natural amino acids of standard nomenclature as listed in J. Biol. Chem., 243:3552-59 (1969) and adopted in 37 C.F.R., section 1.822(b) (2) belong to the group of amino acids listed herein below. Non-natural amino acids are those not listed in the below table.

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